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Transforming Lives Through prime edits
Through ‘Prime Editing’, over 90% of inherited diseases can be targeted and corrected.
DST creating Genomically edited cell lines
1. Prime Editing of iPSCs
Targeting inherited retinal diseases in initial phases. ~80 different gene mutations cause Retinitis Pigmentosa and eventual blindness in patients. What if we created cell banks and expand drug outcomes?
2. Create diseased cell lines
After prime edits confirmed in iPSCs, downstream differentiation into RPE cell monolayers or other neural tissue to study disease progression. Displayed is a RPE monolayer after prime edits.
3. Create Organoids
Creating different organoids and neural tissues will expound our knowledge deep into the cosmos. Displayed is a 150 day retinal organoid after prime edits.
4. Develop Targeted medications
Creating diseased cell lines and organoids will allow researchers to develop innovative therapies. Precision medicine and deep sequencing analysis through long read isoform capture is of interest and progressing forward through NSF grants.
Our Genomic mission
- At Deep Space Therapeutics, we can create diseased cell lines from iPSCs for any researcher to develop drugs or biological interventions in AAV or Lenti viral therapies.